参芪柔肝饮抗肝纤维化临床观察

Observation of Shenqirougan Decoction on Hepatic Fibrosis

目的观察参芪柔肝饮抗肝纤维化的疗效。方法应用参芪柔肝饮治疗慢性乙型肝炎肝纤维化患者36例,并与鳖甲软肝片治疗的36例作对照(两组治疗均在内科常规保肝基础上施行);观察慢性乙型肝炎肝纤维化患者治疗前后的症状、肝纤维化指标、肝功能以及B超等指标的改善情况。结果治疗组总有效率高于对照组,治疗组治疗后肝纤维化、肝功能指标的改善方面亦优于对照组。结论参芪柔肝饮具有良好的抗肝纤维化作用。

Objective： To observe the clinic curative effect of Shenqirougan Decoction in treating the hepatic fibrosis. Methods： This researcb is abided by the principle of random contrast. 36 cases of hepatic fibrosis due to chronic hepatitis B treated Biejiaruangan Pill by was contrasted with 36 cases of the disease treated by Biejiaruangan Pill. These were observed synthetically： clinical symptoms, signs （tiredness, poor appetite, abdominal distention, diarrhea, hypochondriac pain. ）, indices of hepatic fibrosis （PCⅢ, IV- C, HA, LN） and hepatitis B examination. Results： The total rates of efficacy in treatment group was higher than that of the contrast group, and the improvment of the indexes about hepatic fibrosis, liver function, between the two groups, had been significantly different. Conclusion ： Shenqirougan Decoction has better effect of anti - hepatic - fibrosis.