原发性腹膜后肿瘤的病理特征及相关问题探讨

Pathological characteristics of primary retroperitoneal tumor and discussion of its related issues

目的:探讨原发性腹膜后肿瘤(PRT)的病理学特征及其与诊断和治疗的关系。方法:对我院收治的72例经手术治疗的PRT患者的病理检查结果和诊治经过进行分析总结。结果:肿瘤完整切除52例,完整切除率为72.22%,其中联合脏器切除17例;肿瘤部分切除8例;病理取检12例。主要并发症为术中大出血(5例)和术后死亡(2例)。PRT组织来源广泛,包括脂肪、神经、淋巴组织等;大小形态各异,但以长径>5 cm者较多见,占81.94%(59/72);质地分为囊性(26.39%)、囊实性(45.83%)和实性(27.78%),多数有完整的包膜(62.50%);术后病理检查提示肿瘤主要累及的脏器为结肠、小肠和肾脏。结论:掌握PRT的病理学特征对其诊断和手术治疗有重要的指导意义。

Objective： To investigate the role of pathological characteristics of the primary retroperitoneal tumor （PRT） in its diagnosis and treatment. Methods： The clinical data of 72 patients with PRT treated by operation in our hospital from 2001. 1 to 2008.12 was analysed and summarized, including pathology results, diagnosis and treatment. Results： Tumor was completely removed in 52 cases, in a rate of 72.22% （ including 17 cases of multiple organ resection） ; partial resection was performed in 8 cases; investigation biopsy was performed in 12 cases. Major complications were intra-operative hemorrhage （5 cases）, postoperative death （2 cases）. PRT had a variety of tissue origin, including fat, nerve, lymphoid tissue and so on. The size of PRT varied in shape and form, mostly with an axis 〉5 em; PRT presented in cystic （26.39%）, pouch solid （45.83%） and solid （27.78%）, most of them having complete envelopes （62.50%）. Postoperative pathology identified that colon, small intestine and kid- ney were the most frequently invaded organs. Conclusion： Pathological characteristics of PRT can be helpful in its diagnosis and treatment.