高脂血症性急性胰腺炎的临床分析

Clinical Analysis of Acute Hyperlipidemic Pancreatitis

目的探讨高脂血症(HL)与急性胰腺炎(AP)的关系。方法回顾广汉市人民医院2004年1月-2008年12月收治的526例急性胰腺炎患者,分析脂肪肝、高脂血症与急性胰腺炎发病的关系。结果在526例AP中有43例高脂血症性急性胰腺炎(8.17%),与其他原因所致的胰腺炎相比,高脂血症性胰腺炎(HLAP)血甘油三酯(TG)升高明显(P<0.05),血总胆固醇(TC)升高不明显;糖尿病和脂肪肝发病率与其他原因所致的胰腺炎相比差异有统计学意义(P<0.05)。结论高甘油三酯血症和胰腺炎关系密切,是胰腺炎的一个独立危险因素,HLAP与其他原因所致的胰腺炎相比,其糖尿病和脂肪肝发病率明显增高。临床上降脂治疗对HLAP很重要。

Objective To explore the correlation between hyperlipidemia （HL） and acute panereatitis （AP）.Methods The clinical data of 526 cases with AP treated in our hospital from Jan.2004 to Dec.2008 was analyzed retrospectively to evaluate the correlation between AP and fatty liver and HL.Results In 526 cases of acute pancreatitis,there were 43 cases（8.17%） of HLAP.The level of blood TG in HLAP patients was higher（P〈0.05）,but the level of blood TC was normal.There was statistical difference in the incidence of fatty liver and diabetes between HLAP and other kinds of panereatitis （P〈0.05）.Conclusion Serum HTG bears closely correlation to AP,and is an independent dangerous factor for AP.HLAP often coexists in patients with fatty liver and diabetes.To reduce the blood lipid is important for patients with HLAP in clinic.