儿童颈动脉内-中膜厚度与肥胖类型相关性的超声评价

Ultrasonography Evaluation of Correlations between Obesity Phenotypes and Common Carotid Artery Intima-Media Thickness in Children

目的应用超声手段探测儿童颈动脉内膜-中层厚度(IMT),探讨其与儿童肥胖类型的关系。方法依体质指数(BMI)、腰围身高比(WHtR)标准,入组外周性肥胖组160名(A组),内脏性肥胖150名(B组),正常体重儿童160名(正常对照组);应用超声手段探测各组儿童内脏脂肪厚度(VFT)和颈动脉内膜-中层厚度,比较3组间各项检测参数。结果内脏肥胖组VFT、IMT均高于外周性肥胖组及正常组,差异具有统计学意义(P<0.05);外周性肥胖组VFT、IMT与正常组相似,差异没有显著性。结论IMT与肥胖类型相关,内脏性肥胖儿童VFT、IMT增加。实时超声检查技术为研究儿童肥胖类型提供了一种新的检测手段。

Objective To explore the relationship between obesity phenotypes and common carotid artery（CCA） intima-media thickness（IMT） in children measured by Ultrasonography（US）.Methods 310 cases of overweight children and 160 cases of normal weight children were included in this study.All participants were categorized into three groups according to specific body mass index（BMI） and waist-to-height ratio（WHtR）.Namely 160 cases in general obesity（peripheral obesity） group（group A）,150 cases in visceral obesity group（group B） and 160 cases in non-obese group,Each subject underwent transthoratic US to measure visceral fat thickness（VET） and CAA-IMT.Results Data of VET and IMT in group B was significantly higher than that of group A and non-obese group（P〈0.05）;while no VET and IMT differences were observed between group A and non-obese group（P〈0.05）.Conclusion The IMT in children was correlated with the phenotypes of obesity.A significant correlation between VET and IMT is found in our study.The intervention strategy should be implemented as early as possible.