摘要
眼部新生血管性疾病特别是眼后段的新生血管可以导致多种眼部疾病,眼内的新生血管的形成与血管内皮生长因子(VEGF)有关。目前抗VEGF的药物逐渐开始在眼科应用。其中的代表药物有Avastin、Lusentis等。本研究对VEGF在眼部新生血管形成中的作用,以及Avastin的作用机制、眼部适应症和副作用进行综述。
Ocular neovascular diseases,especially posterior segment neovascularization,relate vascular endothelial growth factor(VEGF).Therefore, anti-VEGF drugs are used in eye diseases step by step,Including representatives of drugs Avastin.In this article,it is summarized that the characteristics and angiogenesis of VEGF in neovasctdar disease of eyeball and the mechanism of Avastin in the posterior section of scope of application and side effects.
出处
《疾病监测与控制》
2010年第4期198-201,共4页
Journal of Diseases Monitor and Control