骨髓增生异常综合征相关基因的研究进展
摘要
骨髓增生异常综合征（MDS）是造血干细胞的异质性疾病，至今病因尚未完全清楚。近年来随着分子生物学技术的发展，对MDS相关基因的研究越来越多。研究证实，在MDS患者中存在一系列异常，包括基因甲基化、转录因子的突变和激酶突变等。本文就与MDS发病机制相关的P15INK4b、RUNX1和FHIT等基因的研究进展作一综述。
出处
《国际输血及血液学杂志》
CAS
2010年第2期150-153,共4页
International Journal of Blood Transfusion and Hematology
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