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规范脑恶性胶质瘤治疗的几点建议——有感于《中国中枢神经系统恶性胶质瘤诊断和治疗共识(简化版)》 被引量:4

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摘要 由于脑胶质瘤发病率高,危害大,目前国内各医院对于胶质瘤的诊疗存在不同的看法,诊疗行为很不规范,严重影响我国脑胶质瘤尤其是恶性胶质瘤的整体诊疗效果。为此,2009年中华医学会神经外科分会肿瘤专业组在中华医学杂志发表了《中国中枢神经系统恶性胶质瘤诊断和治疗共识》(以下简称《共识》),希望以此为契机,向全国推广和普及。
出处 《中华医学杂志》 CAS CSCD 北大核心 2010年第15期1079-1080,共2页 National Medical Journal of China
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  • 1Gerson SL. MGMT: its role in cancer aetiology and cancer therapeutics. Nat Rev Cancer 2004; 4: 296-307.
  • 2Watts GS, Pieper RO, Costello JF, Peng YM, Dalton WS, Futscher BW. Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene. Mol Cell Biol 1997; 17: 5612-5619.
  • 3Esteller M, Hamilton SR, Burger PC, Baylin SB, Herman JG. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999; 59: 793-797.
  • 4Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, Vanaclocha V, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000; 343: 1350-1354.
  • 5Hegi ME, Diserens AC, Godard S, Dietrich PY, Regli L, Ostermann S, et al. Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. Clin Cancer Res 2004; 10: 1871-1874.
  • 6Hegi ME, Diserens AC, Gorlia T, Hamou ME de Tribolet N, Weller M, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 2005; 352: 997-1003.
  • 7Stupp R, Mason WE van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005; 352: 987-996.
  • 8Brandes AA, Tosoni A, Cavallo G Reni M, Franceschi E, Bonaldi L, et al. Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study. J Clin Oncol 2006; 24: 4746-4753.
  • 9Esteller M, Gaidano C~ Goodman SN, Zagonel V, Capello D, Botto B, et al. Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma. J Natl Cancer Inst 2002; 94: 26-32.
  • 10Eads CA, Danenberg KD, Kawakami K, Saltz LB, Blake C, Shibata D, et al. MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res 2000; 28: E32.

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