大肠类癌31例诊治分析

Diagnosis and Treatment of Carcinoid,Report of 31 Cases

目的:研究大肠类癌的临床特点及个体化治疗策略。方法:回顾性分析31例大肠类癌患者的临床资料,分析肿瘤大小与生存率及病理分期的关系。结果:31例中30例获得随访,死亡7例,生存期6～40个月,中位生存期15月,5年生存率87.5%(21/24)。类癌直径<1cm、1～2cm、>2cm肿瘤患者的5年生存率分别为100%、85.7%、20.0%,直径>2cm组与另外两组差异有统计学意义(P<0.05)。按TNM病理分期,直径<1cm、1～2cm、>2cm3组肿瘤的T分期与N分期存在差异(P<0.05),肿瘤直径越大T及N分期越晚。结论:肿瘤大小及术前完善检查、准确分期对于大肠类癌的个体化治疗有重要意义。

Objective To study the clinical characteristics and individualized treatment strategies of colorectal carcinoid Methods The clinical data of the 31 patients with colorectal carcinoid（21 Male,10 female,mean age 46.5 years） were analyzed retrospectively.All cases were divided into 3 groups on the basis of the diameter of the tumor,1 cm,2 cm and 3 cm.The relation between tumor size with survival rate and pathologic staging were analyzed.Results Thirty cases were followed up.There were 7 cases died.The life span was from 6 to 40 months,and the median survival time was 15 months.The 5-year survival rate was 87.5%（21/25）.The five-year survival rates of the 3 groups were 100%,85.7%.20% respectively with significant differences（P 〈0.05）.According to the TNM pathologic staging,there were different T stages and N stages among the three groups of carcinoid（P 〈0.05）.The bigger the tumor diameters were,the later the T and N staging were Conclusion The tumor size and the overall preoperative examination and accurate staging were important to the individualized design of treatment for colorectal carcinoid.