广州地区1995～1997年HIV抗体检测情况分析

Analysis of the Test Situation of the Blood Donors HIV Antibody from 1995 to 1997 in Guangzhou

为了解献血员人群ＨＩＶ感染情况，我们对１９９５～１９９７年献血员ＨＩＶ抗体检测情况进行了分析。方法：献血员ＨＩＶ抗体的初筛试验采用抗－ＨＩＶ抗体ＥＬＩＳＡ法，ＨＩＶ抗体初筛试验阳性者用蛋白印迹法（ＷＢ）进行确认。结果：３年内共检测１４００２８人次，初筛ＨＩＶ抗体阳性１８例献血员，并全部经ＷＢ法确认为ＨＩＶ抗体阳性。其中１５例为男性，３例女性，均为来自外省的流动人口。１８例ＨＩＶ抗体阳性献血员中，ＨＣＶ抗体阳性检出率为８３３％（１５／１８），ＨＢｓＡｇ阳性检出率为６１１％（１１／１８），ＨＢｓＡｇ和ＨＣＶ抗体阳性检出率为３３３％（６／８）。结论：在献血员人群中ＨＩＶ抗体阳性检出率呈上升趋势，为此献血员ＨＩＶ抗体筛查对预防和控制输血传播ＨＩＶ具有重要意义。

Objective:\ In order to investigate the situation and distribution of HIV infection in blood donors, this paper analyzed the situation of the blood donors HIV antibody test from 1995 to 1997 in Guangzhou. Methods: \ Serum HIV antibody was detected by ELISA from 140 028 blood donors, and HIV antibody positive in primary screen test had to confirm by WB test. Results: In three years 140 028 blood donors were tested. 18 donors were found as HIV antibody positive by ELISA in the primary screen test. All of them were confirmd as HIV antibody positive. 15 of them are male and 3 of them are female. They are from another province. In the blood donors with HIV antibody positive, HCV antibody positive ratio was 83.3% (15/18), HBsAg positive ratio was 61.1% (11/18), and both of HCV antibody and HBsAg positive ratio were 33.3% (6/18).Conclusion: \ The ratio of the HIV antibody positive are increasing with time in blood donors. Detection of serum HIV antibody by ELISA might be helpful to prevent and control transfusion transmitted AIDS. HBV and/or HCV superinfection were relatively common among blood donors who was infected with HIV.