1例肝癌患者非癌肝组织的病理分析

Pathological Studies on Nontumorous Liver Tissues of 61 Cases with Primary Hepatocellular Carcinoma

对６１例肝癌患者的非癌肝组织进行了病理观察和分析。结果表明：３４例伴有肝硬化，２７例无肝硬化。３４例肝硬化中，活动性肝硬化３２例（占９４１％），２例静止性肝硬化中仍可见单个和灶性肝细胞坏死。２７例无肝硬化患者中，呈慢性活动性肝炎表现者２６例（占９６３％），１例为慢性迁延性肝炎。由此提示：肝癌的临床发展中，既存在慢性肝炎—肝硬化—肝癌的三个阶段，也存在慢性肝炎—肝癌的两个阶段过程。积极治疗肝炎，阻止肝细胞坏死也是预防肝癌的重要手段之一。

Nontumorous liver tissues of 61 cases of primary hepatocellular carcinoma(PHC) were studied.The results revealed that 34 cases had cirrhosis,27 cases had none.In the former group, 32 active cirrhosis (AC) (94 1%) were confirmed.Single and focal hepatocellular necrosis was found in the other 2 cases with silent cirrhosis.In the latter group, 26 cases (96 3%) had chronic active hapatitis (CAH).Only one case had chronic persistent hepatitis.It was suggested that PHC had obvious background of liver disease i.e AC or CAH.Some patients involved in“chronic hepatits-cirrhosis-PHC”.A three stages course in PHC development;and others only in “chronic hepatitis-PHC”Treating hepatitis intensively and stopping hepaticellular necrosis early were very important for PHC prevention.