放宽心脏移植的选择标准治疗终末期心脏病的临床经验分析

Analysis of the Clinical Experience for the Broadening of the Selection Criteria for Heart Transplatation Being Treated End-Stage Heart Disease

为了缓解心脏移植手术的供体严重短缺的矛盾，对原设定的有关供体和受体的选择标准作了适当的放宽。通过对同一心脏中心的８９１例心脏移植手术的治疗效果的分析，发现５２例接受供体年龄大于５５岁的受心者实际生存率与８３９例供体年龄小于５５岁的受心者相比无显著性差别（Ｐ＝０４９）。年龄大于６０岁时１０７例受心者与年龄小于６０岁的受心者实际生存率相比也无显著性差别（Ｐ＝０１０）。因此，在供体和受体的选择标准方面放宽限制。

In the hope of improvement the condition of shortage of donor organs for heart transplatation, the original selection criteria for potential recipients and donors was broadened. Through the analysis of the clinical results for 891 cases that were performed heart transplatation in a single heart center, we found that there was not significant difference in actual survival rate between 52 cases who received a donors from less than 55 years of age and 839 cases from greater than 55 years of age ( P =0.99).Furthermore, there was also not significant differene in actual survival rate between 107 cases who were as recipients from greater than 60 years of age and 784 cases from less than 60 years of age ( P =0.10). Therefore we consider that the heart transplatation provides more effectively treatment for many end-stage heart diseases due to the suitable broadening of selective criteria for potential recipients and donors.