耐甲氧西林金黄色葡萄球菌临床耐药性分析

Clinical drug resistance analysis of MRSA

目的 为预防和控制医院感染的发生,对耐甲氧西林金黄色葡萄球菌的临床分布和耐药性进行分析.方法 使用ATB细菌鉴定分析仪进行细菌鉴定,用纸片扩散法鉴定耐甲氧西林金黄色葡萄球菌,药敏试验用K-B法.结果 在各临床科室中,由耐甲氧西林金黄色葡萄球菌引起的医院感染,ICU的比例最高,下呼吸道是最常见的感染部位,52株耐甲氧西林金黄色葡萄球菌对多种抗菌药物耐药,没有发现耐万古霉素菌株.结论 由耐甲氧西林金黄色葡萄球菌引起的医院感染以ICU病人最多见,以下呼吸道感染为主,耐甲氧西林金黄色葡萄球菌除对万古霉素敏感外对多种抗菌药物耐药.因此,临床医生要合理使用抗菌药物.

Objective To study distribution and drug- resistance of meticillin- resistant S. aureus（MRSA） for the prevention and control of nosocomial infection. Methods Using ATB - expression analyzer identify the microbe, disk - diffusion was used for detecting MRSA, susceptibility test was determined by K- B method. Results The MRSA infection percentage of ICU was the lnghest（26.92% ） in all department. Lower respiratory tract was the most common infection site. 52 strains of MRSA showed general resistance to many kinds of antibiotic drugs, no strains were resistance to vancomycin. Conclusiotts MRSA nosocomial infection usually occurs in the patients of ICU, lower respiratory tract is the most common infection site, MRSA showed multi - resistant characteristic except vancomycin with high sensitivity. So clinic should pay attention to reasonable usage of antibiotic.