老年人空腹血糖受损不同诊断标准比较

Follow-up study on prevalence of impaired fasting glucose with different diagnostic criteria among community elderly people

目的采用1997年及2003年美国糖尿病协会(ADA)标准诊断社区老年人空腹血糖受损(IFG)情况,并随访其对转归的影响。方法2004年,对贵州省贵阳市城区1 645名老年人进行调查,2008年随访2004年空腹血糖正常(normal fasting glucose,NFG)人群IFG的发病情况、IFG转化为糖尿病(DM)情况、IFG患者心血管疾病的发病情况。结果基线人群按2003年ADA标准诊断IFG患病率为22%,按1997年ADA标准诊断IFG患病率为11%,1997年ADA诊断IFG患者高血压与冠心病的患病率高于2003年ADA的标准。2008年随访人群中,2003年ADA标准IFG的发病率为7.3%,1997年ADA标准为3.6%;2种标准诊断为IFG转归构成情况差异有统计学意义。结论IFG对DM的预测有重要作用。不同的标准诊断IFG的患病率不同,4年随访并未显示出其对老年人发生糖尿病、高血压、冠心病不同的预测作用。

Objective To evaluate the effect of different cut-point on impaired fasting glucose（IFG） detection in community elder people.Methods A total of 1645 elderly people were followed-up for detection of IFG,cardiovascular disease,and diabetes mellitus from 2004 through 2008.Results The prevalence rate of IFG was 22% and 11% according to the criteria of American Diabetes Association（ADA） in 2003 and 1997,respectively.The prevalence of hypertension and coronary heart disease diagnosed with the 1997,ADA criteria was higher than that of with 2003 ADA criteria.In 2008,the incidence rate of IFG was 7.3% and 3.6%according to the ADA criteria of 2003 and 1997,respectively,and there was a significant difference in IFG outcomes between subjects diagnosed with different criteria.There was no significant difference in incidence rates of hypertention and coronary heart disease between subjects with and without IFG based on different ADA criteria.Conclusion The IFG is a predictor for diabetes mellitus and different criteria of IFG could result in different IFG prevalence in a same population.