颈动脉狭窄兔模型的DSA与CTA评价

Evaluation on Carotid Artery Stenosis in Rabbit Models by DSA and CTA

目的:探讨粥样硬化性颈动脉狭窄兔模型的DSA及CTA应用价值。材料与方法:通过植入硅橡胶圈于兔颈动脉外膜加胆固醇饲料喂养的40只颈动脉狭窄模型兔,经股动脉插管方法行DSA及CTA检查,观察模型兔颈动脉狭窄程度及影像学征像。结果:DSA技术及CTA的多平面重建(MPR)、曲面重建(CPR)、最大密度投影(M IP)和三维容积漫游(VRT)等技术均可显示兔模型的颈动脉管腔狭窄的部位、形态、范围、程度及颈动脉的血管走向。结论:DSA与CTA均能较好的反应模型兔的颈动脉狭窄部位、形态,DSA能动态观察其血液动力学的变化;CTA既可观察其形态学改变,同时也可观察血管外组织结构。

Purpose：To evaluate the value of DSA and CTA image characteristic changes in 40 rabbit carotid artery stenosis models.Materials and Methods：Experimental atherosclerosis carotid artery stenosis rabbits models were established with insertion of a flexible collar around one carotid artery added to high cholesterol diet for 2 weeks.Models were checked by computed tomography angiography（CTA）and digital subtraction angiography（DSA）.Results：The location,modality,range extent and oriental of stenosis could be revealed by DSA and CTA technique which include MPR,CPR,MIP and VRT.Conclusion：It is feasible to detect carotid artery stenosis by both DSA and CTA,DSA is better than CTA in finding the hemodynamic changes.while CTA is better than DSA in observation of extravasculer structure.