多烯磷脂酰胆碱治疗慢性乙型肝炎合并脂肪肝损害临床疗效观察

Clinical study on the treating of chronic hepatitis B complicated by fatty liver with polyunsaturated phosphatidyl choline phthalate

目的:观察多烯磷脂酰胆碱治疗慢性乙型肝炎合并脂肪肝损害的临床疗效。方法:选择确诊慢性乙型肝炎合并脂肪肝损害63例;随机分为两组。治疗组(n=33)在常规保肝治疗的基础上,加服多烯磷脂酰胆碱胶囊,456mg/次,每日3次;对照组(n=30)常规保肝治疗;两组均4周为1个疗程。结果:两种药物临床总有效率分别为93.9%、66.7%,血清胆红素下降及肝功能恢复治疗组较对照组明显(P<0.05)。结论:多烯磷脂酰胆碱治疗慢性乙型肝炎合并脂肪肝损害,能取得较为满意的疗效,未见明显副作用。

Objective：To discuss the results of treating chronic hepatitis B complicated by fatty liver with polyunsaturated phosphatidyl choline phthalate.Methods：63 cases of chronic hepatitis B patients were selected and divided at random into two groups. The treatment group（n=33） in the conventional treatment based on liver protection,plus clothing polyene phosphatidyl choline capsules phthalate,456 mg /times,three times a day;the control group（n=30） conventional liver treat ment;two groups were four weeks as a course of treatment.Results：Two kinds of drugs of clinical total effective rates were 93.9%,66.7%,decline in serum bilir-ubin and liver function to restore the treatment group than in the control group was significantly（P〈0.05） .Conclusion：It is efficacy and safety of polyunsaturated phosphatidyl-PC treatment of chronic hepatitis B complicated by fatty liver injury in clinical treatment,no obvious side effects.