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猪源抗菌肽的研究进展

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摘要 随着抗生素的广泛应用和耐药性菌株的不断出现,细菌性疾病的预防和治疗再次成为一大难题。目前,临床上应用的大部分抗菌药物的毒副作用很大、容易产生耐药性且价格很高。因此,寻求和研制高效、安全、抗菌谱广、不易产生耐药性、普遍实用的新型抗菌药物成为当今一项新的课题。近年来,具备新型抗菌药物潜在优点的抗菌肽不断被发现,引起研究者的重视,
出处 《中国饲料添加剂》 2009年第3期8-11,共4页 China Feed Additive
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  • 1Patil A A, Cai Y, Blecha F, et al. Cross -species analysis of the mnmmalian β - defeusin gene family: presence of syntenic gane clusters and preferential expression in the male reproductive tract[ J]. Physiol Genomics, 2005, 23:5 - 17.
  • 2Sang Y, Pafil A A, Zhang G, et al. Bioinformatie and expression analysis of novel porcine beta - defensins [J]. Mamm Genome, 2006, 17:332 -339.
  • 3Veldhuizen E J A, Rijnders M, Claassen E A, et al. Porcine β - defensin 2 displays broad antimicrobial activity against pathogenic intestinal bacteria[ J ]. Molecular Immunology, 2008, 45:386 - 394.
  • 4Yu K, Park K, Kang S W, et al. Solution structure of a cathelicidin - derived antimicrobial peptide, CRAMP as determined by NMR spectroscopy [ J ]. J Peptide Res, 2002, 60:1.
  • 5Yang D, Chertov O, Oppenheim J J. The role of mammaliam antimicrobial peptides and proteins in awakening of innate host defenses and adaptive immunity [ J ]. Cell Mol Life Sci, 2001,58:978.
  • 6Agerberth B, Lee J Y, Bergman T, et al. Amino acid sequence of PR - 39: Isolation from pig intestine of a new member of the family of proline - arginine - rich antibacterial peptides [ J ]. Euripean Journal of Biochem- istry , 1991, 202:849 - 854.
  • 7Gudmundsson G H, Magnusson K P, Johansson M, et al. Structure of the gene for porcine peptide antibiotic PR- 39 a cathelin gene family member: Comparative mapping of the.locus for the human peptide antibiotic FALL - 39 [ J ]. Proceedings of the National Academy of Sciences of the USA, 1995, 92:7085 - 7089.
  • 8Ganz T, Lehrer R I. Antimicrobial peptides of verte- brates[J]. Current Opinion In Immunology, 1998, 10: 41 -44.
  • 9Yasuhiko I. PR - 39, a proline/argine - rich antimicrobial peptide, exerts cardioprotective effects in myocardial is chemia - reperfusion [ J ]. Cardiovascular Research, 2001,49:69-77.
  • 10Gennaro R, Zanetti M, Benincasa M, et al. Pro - rich antimicroblal peptides from animals: structure, biological functions and mechanism of action [ J ]. Curt Pharm Des, 2002, 8:763-778.

二级参考文献9

  • 1吴金梅,陈丽颖,王艳玲.抗菌肽的研究进展及应用前景[J].动物医学进展,2005,26(9):27-30. 被引量:16
  • 2吴希,张双全.抗菌肽对细菌杀伤作用的分子机制[J].生物化学与生物物理进展,2005,32(12):1109-1113. 被引量:17
  • 3Zhang G,Wu H,Shi J. Molecular cloning and tissue expression of pBD-1 ,a porcine β-defensin. FEBS Lett, 1998,424:37-40
  • 4Zhang G, Hiraiwa H, Yasue H et al. Cloning and characterization of the gene for a new epithelial β-defensin: genomic structure,chromosomal localization and evidence for its constitutive expression.J Biol Chem,1999, 274: 24031-24037
  • 5Zhang GL, Ross CR, Blecha F. Porcine antimicrobial peptides:new prospects for ancient molecules of host defense. Vet Res ,2000,31: 277 - 296
  • 6Shi JS, Zhang GL, Wu H et al. Porcine epithelial β-defensin 1 is expressed in the dorsal tongue at antimicrobial concentrations.Infection and Immunity, 1999, 67: 3121-3127
  • 7Jeffrey L Bennetzen, Benjamin D Hall. Codon selection in yeast. J Biol Chem, 1982,257:3026 - 3031
  • 8赵翔,霍克克,李育阳.毕赤酵母的密码子用法分析[J].生物工程学报,2000,16(3):308-311. 被引量:192
  • 9罗刚,魏泓.猪防御素基因PBD-I在大肠杆菌中的重组和融合表达[J].遗传,2003,25(2):146-150. 被引量:17

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