尿胰蛋白酶原—Ⅱ测定在急性胰腺炎早期诊断中的应用

Application of Urinary Trypsinogen-Ⅱ in Early Diagnosis of Acute Pancreatitis

目的:探讨尿胰蛋白酶原一Ⅱ测定在急腹症中筛选急性胰腺炎的应用价值。方法:对126例连续就诊的急腹症病人在检测血、尿淀粉酶的同时测定尿胰蛋白酶原一Ⅱ。结果:48例急性胰腺炎中有45例尿胰蛋白酶原一Ⅱ阳性,敏感性为93.8%,78例非胰腺炎的急腹症病人有2例假阳性,特异性为97.4%,其中6例重症急性胰腺炎中尿胰蛋白酶原一Ⅱ全部阳性。结论:尿胰蛋白酶原一Ⅱ是急腹症病人筛选急性胰腺炎快速而简便的方法,具有较高的特异性和敏感性。

Objective：Explore the method,which could find out the acute pancreatitis from abdomen using urinary trypsinogen-Ⅱ.Method： 126 examples of abdomen,which were continuous treated in hospital,were test with urinary trypsinogen-Ⅱ when check the urine amylase and blood at the same time.Results：45 positive patients with urinary trypsinogen-Ⅱ were founded from 48 abdomen cases,and the sensitivity with up to 93.8%.It was found that 2 cases were false positive and 6 cases were positive with urinary trypsinogen-Ⅱ from 78 patients of abdomen,which are non-pancreatitis,and the corresponding specificity was 97.4%.Conclusion：Urinary trypsinogen-Ⅱ is a quick and easy way to screening of acute pancreatitis from abdomen;it could afford highly specificity and sensitivity.