对氨基苯基卟啉镍聚合膜电极电催化测定对乙酰氨基酚

Voltammetric Determination of Acetaminophen by a Electropolymerized Tetra(p aminophenyl)porphyrin Nickel(Ⅱ) Film Electrode

用电化学方法在玻碳电极表面制备了对氨基苯基卟啉镍聚合膜．采用循环伏安法，交流阻抗分析等方法研究了电极的电化学特性．在ＮａＯＨ底液中，聚合膜电极有一对稳定的氧化还原峰，能催化对乙酰氨基酚的电氧化．催化电流与对乙酰氨基酚的浓度在１×１０－６～２×１０－４ｍｏｌ·Ｌ－１范围内呈线性关系．电极用于扑热息痛片中对乙酰氨基酚含量的测定，结果令人满意．

The polymer film of tetra(p-aminophenyl)porphyrin nickel was obtained at glassy carbon electrode by electrochemical method.Cyclic voltammogram of the electrode exhibited two stable redox waves in 0.5mol.L -1 aqueous NaOH solution.The electrochemical characteristics of the electrode were studied by cyclic voltammetry,a.c.impedance analysis and other methods.The oxidation peak current of the film electrode increased with the addition of acetaminophen in the NaOH aqueous medium.The method showed good linearly in NaOH aqueous solution for 1×10 -6 ～2×10 -4 mol.L -1 acetaminophen.The electrode can be used for the determination of acetaminophen in paracetamolum preparation.