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脂肪乳剂对局麻药中毒的复苏效应 被引量:2

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摘要 在实施区域阻滞麻醉时,最严重的并发症莫过于局麻药中毒诱发的心搏骤停,一旦发生,因没有特效救治措施,仅可进行一般性的心肺复苏支持,被动地等待过量的药物从机体排出,往往导致严重后果,甚至患者死亡。在最近的几十年中,由于限定药物最大剂量、规范给药方法等预防措施的采用以及局麻药自身安全性的提高,局麻药中毒的发生率逐年下降,但这一恶性事件并未消除,据报道,外周神经阻滞、硬膜外阻滞时局麻药严重中毒发生率分别为7.5/10000~20/10000、4/10000。
出处 《中华麻醉学杂志》 CAS CSCD 北大核心 2010年第2期132-136,共5页 Chinese Journal of Anesthesiology
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