姜黄素的抗氧化机制及以其为先导物的抗氧化化合物研究进展

Research Progress in Antioxidant Mechanisms of Curcumin and Development of Antioxidant Curcuminoids

姜黄素具有抗氧化、抗肿瘤、抑菌等多种药理活性。近年来为开发姜黄素类抗氧化剂,国内外研究者设计和合成了大量姜黄素衍生物。本文介绍了姜黄素及其衍生物的抗氧化机制,重点概述基于抗氧化的姜黄素抗氧化衍生物的研究进展。

Curcumin has been reported to have many pharmacological activities,such as antioxidant,antitumor,and antibacterial activities.In recent years,a number of curcuminoids have been designed and synthesized to obtain more effective antioxidants.The antioxidant mechanisms of curcumin and its derivatives are discussed,and the research progresses in the synthesis of antioxidant curcuminoids are reviewed in this paper.