奥美拉唑联合用药致心前区疼痛1例用药分析

Analysis on One Case of Percardial Pain Induced by Drug Combination of Omeprazole

目的:为临床联合用药提供参考。方法:通过对2009年12月2日以"高血压病3级、冠心病、慢性支气管炎急性发作"收治的1名79岁男性患者,在应用注射用奥美拉唑钠治疗过程中心前区疼痛的观察和治疗,提出临床应用奥美拉唑出现的不良反应及应对措施。结果与结论:奥美拉唑与其它药物联用易引起心前区疼痛的不良反应。因样本有限,普遍性有待进一步证实。

OBJECTIVE：To analyze one case of pericardial pain induced by drug combination of omeprazole so as to provide reference for drug combination in the clinic. METHODS：A 79-year-old male patient was admitted because of stage Ⅲ hypertension,coronary heart disease,acute attack of chronic bronchitis in Dec. 2 of 2009. He was treated with omeprazole and pericardial pain was observed during treatment. ADR caused by omeprazole were put forward in the clinic. RESULTS CONCLUSION： Omeprazole combined with other drugs can easily cause ADR for example,pericardial pain. The universality of ADR induced by drug combination of omeprazole should be further confirmed because of limited sample.