摘要
目的:评价MR扩散张量成像技术在不同级别胶质瘤、脑膜瘤及转移瘤周围正常脑白质区的应用价值。方法:对43例颅内肿瘤患者行常规MRI及扩散张量成像检查,其中高级别胶质瘤12例,低级别胶质瘤10例,脑膜瘤12例、转移瘤9例。测量瘤周正常脑白质的FA值及对侧相应解剖部位正常脑白质的FA值,行组间统计学分析。结果:高级别胶质瘤瘤周正常脑白质FA值低于对侧正常脑白质FA值,差异有统计学意义(P<0.05);低级别胶质瘤、脑膜瘤及转移瘤FA值的差异无统计学意义。高级别胶质瘤瘤周正常脑白质FA值与低级别胶质瘤、脑膜瘤、转移瘤瘤周正常脑白质之间差异有统计学意义,后三者之间的差异比较无统计学意义。结论:MR扩散张量成像技术有助于颅内肿瘤的定性诊断及推测肿瘤细胞的浸润范围。
Objective:To assess the value of MRI diffusion tensor imaging in the peritumoral white matter areas of different-grade neurogliocytomas、meningomas and metastases.Methods:Forty-three patients with intracranial tumors,including twelve high-grade gliomas,ten low-grade gliomas,twelve meningomas and nine metastases,underwent respectively conventional MR and diffusion tensor MR imaging.FA values were measured in the normal-appearing white matter adjacent to the tumors and contralateral normal white matter,and then interclass statistical analysis was made.Results:FA values of the normal-appearing white matter adjacent to the high-grade gliomas were lower than those of the contralateral normal white matter.The differences were of statistical significance,while there were no differences between the normal-appearing white matter adjacent to the tumors and contralateral normal white matter of low-grade gliomas,meningomas and metastases.FA values of the normal-appearing white matter adjacent to the tumors were different statistically compared with high-grade gliomas and low-grade gliomas,meningomas,and metastases,while the last three had no differences between each other.Conclusion:The application of DTI and the measurement of FA values of the normal-appearing white matter adjacent to the tumors can be helpful for the differential diagnosis of intracranial tumor,also can conclude brain invasion in the normal-appearing white matter adjacent to the high-grade gliomas.
出处
《放射学实践》
北大核心
2010年第4期367-370,共4页
Radiologic Practice
关键词
磁共振成像
扩散张量成像
脑肿瘤
Magnetic resonance imaging
Diffusion tensor imaging
Brain neoplasms