广东地区2782例妇女高危型人乳头瘤病毒感染阳性率和年龄段的关系

The relationship between high-risk human papilloma virus infection rate and different age groups in 2782 women in Guangdong region

目的探讨广东地区妇女高危型人乳头瘤病毒(high-risk human papilloma virus,HR-HPV)感染的阳性率和各年龄段的关系。方法回顾性分析2007年10月到2008年11月在本院妇科门诊就诊的妇女2782例。用实时多重荧光PCR技术对13种HR-HPV进行检测,将筛查人群分为8个年龄段,分别计算阳性检出率,分析HR-HPV的阳性检出率和年龄段的关系,并以年龄段和阳性率的关系作图加以分析。结果在2782例中共检出HR-HPV564例阳性,阳性率为20.3%。HR-HPV的感染阳性检出率和年龄段相关,分别为36～40岁和46～50岁的两年龄段阳性检出率高。结论广东地区妇女HR-HPV的阳性检出率和年龄段相关,且以36～40岁和46～50岁的两年龄段阳性检出率高。

Objective To investigate the relationship between high-risk human papilloma virus infection rate and different age groups in Guangdong region. Methods Retrospective analysis of 2782 female patients who visit gynecology outpatient clinic in our hospital from Oct. 2007 to Nov. 2008 was done. 13 types HR-HPV were tested by the real-time fluorescent PCR （RT-PCR）. The subjects were divided into 8 age groups,and the positive rate was calculated. The relationship between HR-HPV positive rate and age group was analyzed by figure illustration. Results 564 in 2782 cases were positive,with 20.3% positive rate. The HR-HPV positive rate is related to different age group,with the highest rate for two age groups：36～40 years old and 46～ 50 years old. Conclusion The HR-HPV positive rate is related to age group of women,which of the two age groups：36～40 years old and 46～50 years old,have the highest positive rate in Guangdong region.