剖宫产术患者蛛网膜下腔布比卡因混用舒芬太尼与芬太尼效果的比较

A comparative study on the effection of subarachnoid anesthesia with bupivacaine mixed with sufentanil and with bupivacaine mixed with fentanyl in patients undergoing cesarean section

目的评价舒芬太尼混合布比卡因用于剖宫产术患者蛛网膜下腔阻滞的效应。方法择期剖宫产术患者40例,随机双盲分为2组,A组为舒芬太尼组,蛛网膜下腔注射布比卡因10mg混合舒芬太尼10μg;B组为芬太尼组,蛛网膜下腔注射布比卡因10mg混合芬太尼25μg,观察指标为:①感觉阻滞效果;②运动阻滞效果;③胎儿娩出Apgar评分。结果舒芬太尼组的感觉阻滞效果优于芬太尼组,呼吸抑制等不良反应2组差异无统计学意义。结论舒芬太尼混合布比卡因用于剖宫产术患者蛛网膜下腔注射的感觉阻滞效果优于芬太尼混合布比卡因的感觉阻滞效果,其呼吸抑制等不良反应2组差异无统计学意义。

Objective To evaluate the effection of subarachnoid anesthesia with bupivacaine mixed with Sufentanil in patients undergoing cesarean section. Methods Forty patients undergoing elective caesarean section were randomly divided into two groups： patients in group A were received lOmg bupivacaine ＋ 10 μg sufentanil ＋10% glucose 2 ml; patients in group B were received 10 mg bupivacaine ＋ 25 μg fentanyl ＋10% glucose 2 ml. The degree of sensory block and motor block, and the apgar score of the infants were detected. Results The effection of sensory block in patients of group A was significantly was batter than that in patients of group B, but there was no difference between the 2 groups for the side effect, such as respiratory depression. Conclusions The degree of sensory block with bupivaeaine mixed with Sufentanil was higher than with bupivacaine mixed with fentanyl in patients undergoing cesarean section, hut there was no difference between the 2 groups for the side effect, such as respiratory depression.