碘造影剂引起严重副反应的回顾性分析

Retrospective analysis of severe adverse reaction induced by iodine contrast media

目的分析碘造影剂引起的严重副反应的临床病例,探讨其作用机理。方法收集22 682例使用离子型和非离子型碘造影剂病例,进行回顾性分析。结果离子型造影剂发生严重过敏性休克4例,截瘫1例;非离子型造影剂发生严重过敏性休克3例。结论离子型和非离子型碘造影剂均可引起严重的副反应,加用地塞米松不能完全避免副反应的发生。

Objective To analyze the adverse reaction of iodine contrast media and to investigate its mechanism. Methods To retrospectively analyze 22 682 cases who were injected ionic and nonionic io- dine contrast media. Results 4 patients had severe allergic shock in ionic contrast media group, 1 patient had paraplegia,and 3 patients had severe allergid shock in nonionic contrast media group. Conclusion Both ionic and nonionic iodine contrast media can have severe adverse reaction. Administration of contrast media with dexamethasone can not absolutely prevent from adverse reaction.