17例全肝和9例活体肝移植术后感染病原菌分析

Analysis of infection pathogens after full liver transplantation and living donor liver transplantation

目的:通过研究全部以及部分肝移植术后感染的病原菌分布等特点,探讨肝移植术后抗感染的有效治疗方式。方法:采用26例肝移植患者术后送检的血液经细菌常规培养、真菌培养所分离出的病原菌进行分析。结果:17例全肝移植术后细菌性感染的发生率为94.1%,病原菌中革兰阴性杆菌占72.4%,9例活体肝移植患者感染发生率88.9%,革兰阳性球菌53.99%。结论:肝移植术后常会出现细菌感染,但活体肝移植患者以革兰阳性球菌感染为主,而全肝移植以革兰阴性杆菌为主,本研究认为,相对而言,活体肝移植患者术后感染较易控制。

Objective：To explore the effective anti--infection therapy by studying main infection pathogens after complete and partial liver transplantation. Methods：The bacterial culture and fungi culture of blood from 26 eases of liver transplantation were performed from which pathogenic bacteria were separated and analyzed. Results：The incidence of bacterial infection after full liver transplantation was 94.1%, and the gram negative bacilli accounted for 72.4 %. The incidence of bacterial infections after living donor liver transplantation was 88. 9 % ,and the gram positive cocci accounted for 53. 99%. Conclusion-The bacteria infection often occurs after liver transplantation. The main pathogenic organisms of infection were gram positive cocci after living donor liver transplantation, and the main pathogenic organisms of infection were gram negative bacilli after full liver transplantation. In contrast, the postoperative infection after living donor liver transplantation is more easily controlled.