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盐酸莫西沙星序贯治疗中重度社区获得性肺炎疗效与经济学评价 被引量:6

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摘要 目的观察盐酸莫西沙星序贯治疗中重度社区获得性肺炎的疗效。方法62例中重度社区获得性肺炎患者随机分为莫西沙星序贯治疗组和对照组各31例,序贯治疗组给予莫西沙星注射液0.4 g静脉注射,qd;待患者临床症状改善后(一般3~5 d)改为口服莫西沙星片0.4 g,qd,总疗程7~10 d;对照组给予莫西沙星注射液0.4 g静脉注射,qd,总疗程7~10 d。分别观察两组临床疗效、痰细菌清除率、不良反应,并进行成本、效果分析。结果序贯治疗组和对照组临床总有效率分别为83.9%和90.3%,细菌清除率分别为82.6%和81.8%,住院总费用分别达到6 656.1和8 019.2元,两组住院时间差异无显著性,序贯治疗组住院费用更少(P<0.05 )。结论莫西沙星治疗中重度社区获得性肺炎疗效确切,安全性好。序贯疗法可以降低患者医疗费用,成本/效果均优于全程静脉给药,推荐作为中重度社区获得性肺炎的优选治疗方案。
出处 《医药导报》 CAS 2010年第5期686-687,共2页 Herald of Medicine
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