微生态调节剂预防机械通气患者继发腹泻的临床疗效

Clinical efficacy of microecological doses of mechanical ventilation in patients with secondary diarrhea

目的探讨预防性应用微生态调节剂对机械通气患者继发腹泻的防治效果。方法将88例机械通气患者随机分成实验组和对照组。两组患者均给予鼻饲瑞先,实验组在此基础上给予微生态调节剂1周。观察两组患者腹泻发生率和菌群失调情况并分类,测定鼻饲当天和第8天粪便中分泌型IgA,比较两组患者EN达到目标供给量和营养支持的时间。结果实验组腹泻和菌群失调发生率、肠内营养液达到目标供给量的时间均明显低于对照组(P<0.01),而鼻饲第8天实验组粪便中分泌型IgA含量比对照组明显升高(P<0.01);达到目标供给量的时间显著缩短(P<0.01)。结论微生态制剂可有效防止肠道菌群失调,降低ICU患者肠内营养并发腹泻的发生率。

Objective To explore the prophylactic use of microccological agents on mechanical ventilation in patients with diarrhea secondary control effect. Methods Eighty-nine patients with ICU were divided into treatment group（ n = 44 ）and control group（ n = 44 ） at random. The patients were infused with enteral nutrition emulsion or treatment group lemented cntcral nutrition emulsion/or 7 days. Results The incidence rate of diarrhea in the treatment group was 9. 68%, and the incidence rate of diarrhea in the control group was 35.65 % （P 〈 0. 05 ）. The incidence of infections was significantly lower in the treatment group than in the control group. The patients with Intestinal microt＂Iora disorders in the treatment group were less than in the normal and control group ; The time to reach standard amount in the treatment group was significantly less than that in the control group （P 〈 0. 01 ）. Conclusion postoperative enteral nutrition plus microecop harmaeeutics can reduce the rate of diarrhea and shorten the time to reach the standard amount in elderly patients with EN.