调节性T淋巴细胞在烧创伤及脓毒症中的免疫调节作用研究进展
摘要
过去30年里，医学界对烧（创）伤和脓毒症的细胞免疫研究主要集中在巨噬细胞、中性粒细胞以及T、B淋巴细胞等。调节性T淋巴细胞（regulatory Tlymphocyte，Treg）也在免疫调节中扮演重要角色，这类细胞主要包括CD4^＋CD25^＋Treg、
出处
《中华烧伤杂志》
CAS
CSCD
北大核心
2010年第2期124-127,共4页
Chinese Journal of Burns
基金
国家自然科学基金（30730091）
参考文献26
-
1Collison LW,Workman CJ,Kuo TT,et al.The inhibitory cyto-kine IL-35 contributes to regulatory T-cell function.Nature,2007,450(7169):566-569.
-
2Vignali D.How many mechanisms do regulatory T cells need? Eur J Immunol,2008,38(4):908-911.
-
3Caramalho I,Lopes-Carvalho T,Ostler D,et al-Regulatory T cells selectively express toll-like receptors and are activated by li-popolysaccharide.J Exp Med,2003,197(4):403411.
-
4Murphy TJ,Ni Choileain N,Zang Y,et al.CD4 + CD25 + regulatory T cells control innate immune reactivity after injury.J Immunol,2005,174(5):2957-2963.
-
5Ni Choileain N,MacConmara M,Zang Y,et al.Enhanced regulatory T cell activity is an element of the host response to injury.J Immunol,2006,176(1):225-236.
-
6MacConmara MP,Maung AA,Fujimi S,et al.Increased CD4 + CD25 + T regulatory cell activity in trauma patients depresses protective Th1 immunity.Ann Surg,2006,244(4):514-523.
-
7Saito K,Wagatsuma T,Toyama H,et al.Sepsis is characterized by the increases in percentages of circulating CD4 + CD25 + regulatory T cells and plasma levels of soluble CD25.Tohoku J Exp Med,2008,216(1):61-68.
-
8Heuer JG,Zhang T,Zhao J,et al.Adoptive transfer of in vitro-stimulated CD4 + CD25 + regulatory T cells increases bacterial clearance and improves survival in polymicrobial sepsis.J Immunol,2005,174(11):7141-7146.
-
9Scumpia PO,Delano MJ,Kelly KM,et al.Increased natural CD4 + CD25 + regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis.J Immunol,2006,177(11):7943-7949.
-
10Wisnoski N,Chung CS,Chen Y,et al.The contribution of CD4 + CD25 + T-regulatory-cells to immune suppression in sepsis.Shock,2007,27(3):251-257.
-
1唐佳俊,郇京宁.内皮细胞微粒与创伤脓毒症关系研究进展[J].中华烧伤杂志,2010,26(1):26-29. 被引量：1
-
2谢晓繁,贾赤宇.胰岛素在烧伤创面愈合中的作用[J].中华创伤杂志,2006,22(6):475-477. 被引量：11
-
3黄跃生,杨宗城,黎鳌.多器官衰竭防治的研究进展[J].中华整形烧伤外科杂志,1994,10(5):391-393. 被引量：2
-
4闫柏刚,任小宝,赵晓东,李华,刘薇,赵文凤.胰岛素强化治疗对严重烧创伤患者胰岛素抵抗的影响[J].中华烧伤杂志,2013,29(2):181-184. 被引量：3
-
5夏照帆,王钟山,房贺.烧创伤相关肺损伤系统控制技术的研究与转化[J].中华烧伤杂志,2013,29(2):113-115. 被引量：6
-
6陆翔,赖永榕.类风湿关节炎CD4^+CD25^+调节性T细胞的表达及其与病情关系探讨[J].广西医科大学学报,2009,26(2):229-231. 被引量：6
-
7孙雨梅,张彦明,何广胜,陆沭华,韩雪花,崔红霞.CD4^+CD25^+调节性T细胞在特发性血小板减少性紫癜患者中的变化及意义[J].临床血液学杂志,2008,21(5):469-470. 被引量：11
-
8冯永强,王德昌,王坤,冷向锋,肖虎,郭丹凤.烫伤大鼠肠系膜淋巴结T淋巴细胞亚群及细胞凋亡变化[J].中华烧伤杂志,2011,27(2):115-116. 被引量：3
-
9WeiHong-shan LuHan-ming LiDing-guo ZhanYu-tao WangZhi-rong HuangXin.The Regulatory Role of AT 1 Receptor on Activated HSCs in Hepatic Fibrogensis： Effects of RAS Inhibitors on Hepatic Fibrosis Induced by CCI4[J].胃肠病学,2000,5(B08):125-125. 被引量：1
-
10何金根,潘家华,楼皖玲,刘辉.维生素A和布地奈德对哮喘大鼠外周血T细胞亚群和调节性T细胞的影响[J].蚌埠医学院学报,2011,36(5):452-455. 被引量：2
