枣庄地区小儿大叶性肺炎流行病学调查及病原学研究

Epidemiological Survey and Etiological Study in Children with Lobar Pneumonia in Zaozhuang Region

目的:探讨大叶性肺炎病原学特点及流行规律。方法:山东枣庄地区2006年1月—2008年11月住院患儿296例,于入院当日给予吸痰做痰培养,查结核杆菌,查肺炎支原体、衣原体DNA以及呼吸道合胞病毒、腺病毒、流感病毒、副流感病毒和柯萨奇病毒。结果:296例患儿中病原阳性数共179例(60.5%),其中支原体DNA阳性76例(占病原阳性数的42.5%)。流行季节支原体以11月至次年4月为主;病毒及细菌以6～8月为主。发病年龄1～7岁为主,占59.7%。结论:枣庄地区小儿大叶性肺炎病原种类多,以支原体为主,在临床诊治中应加强实验室检查;流行季节集中于寒冷及高温季节。

Objective：To investigate the epidemiology and etiology of lobar pneumonia.Methods：There were 296 cases of children hospitalized in Zaozhuang region from January 2006 to November 2008 enrolled. Tubercle bacillusnurture,Mycoplasma pneumoniae,Chlamydia DNA,and five viruses were tested on the date of admission. Results：The cases of children with mycoplasma DNA positive were 76 cases （accounting for 42.5% of the number of pathogen-positive）. Epidemic season of Mycoplasma was from November to April of the following year,viruses and bacteria was from June to August mainly; Age of onset of lobar pneumonia was from 1 to 7 years old,accounting for 59.7%. Conclusions：There were many kinds of pathogen in children with lobar pneumonia in Zaozhuang region,however mycoplasma was the mainly etiology. The epidemic season was to mainly in the cold and hot seasons.