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提高转基因植物标记基因安全性策略的研究进展 被引量:24

Strategies on the Safety of Selectable Marker Genes in Transgenic Plant
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摘要 目前,广泛使用的转基因植物抗性标记基因对环境和食品存在潜在风险。提高转基因植物标记基因安全性策略有3种:利用无争议的生物安全标记基因;剔除转基因植物中选择标记基因;利用无选择标记基因的转化系统。本文综述了这3种策略的作用原理、种类和存在的问题,并对提高转基因标记基因安全性技术途径的前景和研究方向进行了分析。 Selectable marker genes encoding antibiotic and herbicide are widely used in transgenic plants and have a potential risk to the environment and human health. Currently, there are three kinds of strategies to improve security in using marker genes in transgenic plants: One approach is to develop the use of uncontested biosafety marker genes, the second is to use transgenic plants-removed selectable marker genes and the third is the use of non-selective marker gene transformation system. In this review, each of the strategy principles and problems are highlighted. Moreover, the perspectives are discussed to improve the safety of selectable marker genes in transgenic plants.
出处 《中国农业科学》 CAS CSCD 北大核心 2010年第9期1761-1770,共10页 Scientia Agricultura Sinica
基金 国家转基因生物新品种培育重大专项(2009ZX08003-019B 2008ZX08003-005 2008zx08004-001) 科技部农业科技成果转化项目(2006GB2A100013)
关键词 选择标记基因 转基因植物 生物安全性 selectable marker genes transgenic plant bio-safety
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参考文献64

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