4STARSKA K,BRYS M,FORMA E,et al.Impact of EGFR immunoexpression on STAT3 activation and association with proinflammatory/regulatory cytokine pattern in laryngeal squamous cell carcinoma[J].Oncol Rep,2009,21(2):539-548.
6XIAN J,LIN Y,LIU Y,et al.Combined p14ARF and antisense EGFR potentiate the efficacy of adenovirus-mediated gene therapy in laryngeal squamous cell carcinoma (LSCC)[J].DNA Cell Biol,2007,26(2):71-79.
7AHMED W A,SUZUKI K,IMAEDA Y,et al.Ki-67,p53 and epidermal growth factor receptor expression in early glottic cancer involving the anterior commissure;treated with radiotherapy[J].Auris Nasus Larynx,2008,35(2):213-219.
8JIANG H,YANG B B.p53,epidermal growth factor receptor and proliferating cell nuclear antigen in laryngeal squamous cell carcinoma are not predictive markers for the effect of adjuvant radiotherapy[J].Acta Otolaryngol,2009,129(1):101-107.
9LIU B,REN Z,SHI Y,et al.Activation of signal transducers and activators of transcription 3 and overexpression of its target gene cyclin D1 in laryngeal carcinomas[J].The Laryngoscope,2008,118(11):1976-1980.
10FU Z J,MA Z Y,WANG Q R,et al.Overexpression of cyclin D1 and underexpression of p16 correlate with lymph node metastases in laryngeal squamous cell carcinoma in chinese patients[J].Clin Exp Metastasis,2008,25(8):887-892.
4[1]Spafford MF,Koeppe J,Pan Z,et al.Correlation of tumor marker p53,bcl-2,CD34,CD44H,CD44V6 and Ki-67 with survival and metastasis in laryngeal squamous cell carcinoma.Arch Otolaryngol Head Neck Surgery,1996,122:627-632.
5[3]Sherr CJ,Roberts JM.CDK inhibitors:positive and negative regulator of G-phase progression.Genes Dev,1999,13:1501-1512.
6[8]Segas JV,Lazaris AC,Nikolopoulos TP.et al.Cyclin D1 protein tissue detection in laryngeal cancer.ORL J Otorhinolaryngol Relat Spec,2005,67:319-325.
7[9]Nakashima T,Clayman GL.Antisense inhibition of cyclin D1 in human head and neck squamous cell carcinoma.Arch Otolaryngol Head Neck Surg,2000,126:957-961.
8[10]Fire A,Xu S,Montgomery MK,et al.Potent and specific genetic interference by double-stranded RNA in caenorhabditiselegans.Nature,1998,391:806-811.
9[11]Kudo Y,Kitajima S,Ogawa I,et al.Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27degradation.Mol Cancer Ther,2005．4:471-476.
10[12]Salvi A,Arici B,De Petro G,et al.Small interfering RNA urokinase silencing inhibits invasion and migration of human hepatocellular carcinoma cells.Mol Cancer Ther,2004,3:671-678.
2Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, et al. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies[J]. Cancer Res, 2007, 67(6): 2643-2648.
3Raufiman JP, Shant J, Guo CY, et al. Deoxycholyltaurine rescues human colon cancercells from apoptosis by activating EGFR-depen- dent P13K/Akt signaling[J]. J Cell Physiol, 2008, 215(2): 538-549.
4Hirsch FR, Varella-Garcia M, Burro PA Jr, et al. Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis[J]. Clin Oncol, 2003, 21 (20): 3798-807.
5Jiang H, Yangb B.P53, epidemal growth factor receptor and proliferating cell nuclear antigen .in laryngeal squamous cell carcinoma are not predictive markers for the effect of adjuvant radiotherapy[J]. Acta Otolaryngol, 2009, 129(1): 101-107.
6Kourel Is K, Papadas T, Vandoros G, et al. Glottic versus supraglottic tumors: differential molecular profile [J]. Eur Arch Otorhinolaryngol, 2008, 265(1): 79 - 84.
7Chua DT, Nicholls JM, Au GK, et al. Prognostic value of epidermal growth factor receptor expression in patients with advanced stage nasopharyngeal carcinoma treated with induction chemotherapy and radiotherapy[J]. Int J Radiat Oncol Biolphys, 2004, 59(1): 11-20.
8Burtness B, Goldwasser MA, Flood W, et al. Phase Ⅲ randomized trail of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an eastern cooperative oncology group study[J]. ClinOncol, 2005, 3(34): 8646-8654.
9E.-H.Tan, C.Goh, W.T.Lim, et al. Getitinib,cisplatin,and concurrent radiotherapy for locally advanced head and neck cancer: EGFR FISH, protein expression,and mutational status are not predictive biomarkers [J]. Annals of Oncology advance access, 2011, 6(18): 1-6.
10Abmed W A, Suzukik, Maeda Y, et al. Ki-67,p53 and epidemal growth factor receptor expression in early glottic cancer involving the antenior commissure; treated with radiotherapy [J]. Auris Nasus Larynx, 2008, 35(2): 213-219.
