超声动态监测兔肾缺血再灌注时肾主动脉的血流动力学变化

ULTRASONIC MONITOR OF MASTER RENAL ARTERY HEMODYNAMIC CHANGES IN RENAL ISCHEMIA-REPERFUSION

目的:观察兔在缺血再灌注时,其肾主动脉血流动力学变化特点。方法:运用频谱多普勒超声测定12只成年日本大白兔肾缺血再灌注前、及再灌注后2h、8h、24h肾主动脉收缩期峰值流度(Vmax)、舒张末期流度(Vd)、时间平均血流速度(TAMAX)、搏动指数(PI)、阻力指数(RI)。结果:与缺血再灌注前比较,兔肾主动脉血流动力学在缺血再灌注2h、8h无明显变化,再灌注24h肾主动脉Vmax升高、PI和RI增大(P<0.05),而Vd及TAMAX无明显变化。结论:频谱多普勒超声动态监测兔肾缺血再灌注时,其肾主动脉血流动力学在再灌注24h时方有明显变化。

Objective：To observe the characteristics of master renal artery （MRA） hemodynamic changes in renal ischemia-reperfusion of rabbits.Methods：The spectral Doppler was performed to measure the peak-systolic velocity（Vmax）、end-diastolic velocity（Vd）、time average velocity（TAMAX）、pulsatility index（PI）、 resistance index （RI） of master renal artery on 12 adult Japanese white rabbits with that renal ischemia-reperfusion,before and after 2h、8h、24h after reperfusion.Results：Compared with that before the renal ischemia-reperfusion,2h and 8h after reperfusion the artery hemodynamics had no significant changes,24h after reperfusion the Vmax、PI and RI significantly increased,while the Vd and TAMAX had no significant changes.Conclusion：Using spectral Doppler to monitor renal ischemia-reperfusion of rabbits,there are significant changs in master renal artery hemodynamics after 24h reperfusion.