呋喃唑酮及片剂含量测定方法的改进

Improvement of content determination of furazolidone and furazolidone tablets

目的：改进呋哺唑酮及片剂的含量测定方法。方法：采用紫外分光光度法，在367nm的波长处进行测定，以对照品法计算呋喃唑酮及其片剂的含量。结果：呋喃唑酮在1．6～16μg/ml浓度范围内线性关系良好，A=7．53×10^-2 C＋2．2×10^-3，r=0．9999（n=5）；片剂的平均回收率（n=9）为100．9％。结论：本方法更准确，可作为呋喃唑酮及其片剂的质量控制方法。

Objective ：To improve the method for content determination of furazolidone and furazolidone tablets. Methods：The content is determined by UV spectrophotometic method with detection wavelength of 367 nm. Results ： The linear range of furazolidone was 1.6 - 16 μg/ml,A = 7.53 × 10^-2 C ＋ 2. 2 × 10^-3, r = 0. 999 9 （ n = 5 ） ;The average recovery （ n = 9 ） was 100.9%. Conclusion：This method is accurate and can be applied to determine the content of furazolidone and furazolidone tablets.