药学干预对喹诺酮类药物使用情况的影响

Effect of pharmaceutical care program on use of quinolones

目的:调查药学干预前后氟喹诺酮类药物的使用情况和耐药率。方法:采用回顾性调查与前瞻性结合的方法,比较干预前后氟喹诺酮类药物使用例数以及耐药率的变化。结果:干预前后左氧氟沙星和环丙沙星用于围手术期预防用药和治疗用药使用率大幅度下降。结论:药学干预围手术期氟喹诺酮类药物预防术后感染不仅效果明显且价格低廉。

Objective： To survey the utilization of quinolones and antimicrobial resistance before and after pharmaceutical care. Method： The prospective monitoring and retrospective investigation were applied to compare the number of the cases of quinolone use and antimicrobial resistance rate before pharmaceutical care with those that after pharmaceutical care program. Result： The preventive and treatment usage of levofloxaein and ciprofloxacin during perioperative time was decreased significantly since the pharmaceutical care was carried out. Conclusion ： The pharmaceutical care was an effective and economic way for the rational use of quinolones during perioperative time for the prevention and treatment of postoperative infection.