三种给药方案治疗原发性高血压病的成本效果分析

Costeffectiveness analysis of three oral therapeutic schemes in treatment of hypertension

目的:分析评价三种给药方案治疗原发性高血压的疗效及成本-效果比。方法:运用药物经济学原理对三种给药方案,A:替米沙坦片+氨氯地平片,B:福辛普利钠+硝苯地平控释片,C:依那普利+硝苯地平缓释片进行成本-效果分析。结果:A、B、C三组成本分别为177.52、266.56和65.80元;有效率分别为88.89%、90.00%和74.63%;成本-效果比分别为199.68、296.18和88.17;A、B组对于C组的增量成本-效果比分别为783.45和1306.18。结论:A组方案较佳。

Objective ： To investigate the cost - effectiveness of three oral therapeutic schemes in the treatment of hypertension. Methods： Cost - effectiveness analyses were made for three therapeutic schemes by using pharmacoeconomic principle. Scheme A was telmisartan tablets and amlodipine tablets, Scheme B fosinopril sodium and nifedipine controlled -release tablets and Scheme C enalapril and nifedipine sustained release tablets. Results： The total costs for Scheme A, B and C were 177.52 yuan,266.56 yuan and 65.80 yuan respectively;the effective rates were 88.89% ,90.00% and 74.63% respectively;the cost - effectiveness ratios were 199.68,296.18 and 88.17 respectively. Compared with Group C, the incremental costs -effeetiveness ratios for Scheme A and B were 783.45 and 1 306.18 ,respectively. Conclusions： Scheme A is more preferable to the other two schemes in terms of cost - effectiveness.