期刊文献+

血管内皮生长因子、内皮抑素与冠心病的关系 被引量:5

Vascular Endothelial Growth Factor Endostatin and Coronary Heart Disease
下载PDF
导出
摘要 血管内皮生长因子、内皮抑素是影响血管内皮功能的两个重要因素,它们的动态正负调节影响了冠心病的发生发展。现就其与冠心病的关系作一综述。 Vascular endothelial growth factor (VECF) and endostatin (ES) are two important factors to regulate the vascular endothelial function. They have dynamic positive/negative influence on the origination and development of coronary heart disease (CHD). Here is a review of the relationship between VEGF, ES and CHD.
作者 孔菁 毛威
出处 《实用心脑肺血管病杂志》 2010年第4期524-526,共3页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 血管内皮生长因子 内皮抑素 冠心病 Vascular endothelial growth factor Endostafin Coronary heart disease
  • 相关文献

参考文献23

  • 1Ferrara N,Henzel WJ.Pituitary follicular cells secrete a novel heparin-binding growth factor specific vascular endothelial cells[J].Biochem Biophys Res commun,1989,161 (2):851-858.
  • 2O'Reilly MS,Boehm T,Shing Y,et al.Endostatin:an endogenous inhibitor of angiogenesis and tumor growth[J].Cell,1997,88 (2):277-285.
  • 3Miosge N,Sasaki T,Tim PIR.Angiogenesis inhibitor endestatin is a distinct component of elastic fibers invessel walls[J].Faseb J,1999,13 (13):1743-1750.
  • 4Zachary I,Mathur A,Yla-Herttoala S,et al.Vascular protection:A novel,nonangiogenic cardiovascular role for vascular endothelial growth factor[J].Arterioscler Thromb Vasc Biol,2000,20 (6):1512-1520.
  • 5Abdollahi A,Hlatky L,Huber PE.Endostatin:the logic of antiangiogenic therapy[J].Drug Resist Updat,2005,8 (1-2):59-74.
  • 6Abdollahi A,Hahnfeldt P,Maercker C,et al.Endostatin's antiangiogenic signaling network[J].Mol Cell,2004,13 (5):649-663.
  • 7Inoue M,Itoh H,Ueda M,et al.Vascular endothelial growth factor(VEGF) expression in human coronary atheresclerotic lesions:possible pathophysiological significance of VEGF in progression of atherosclerosis[J].Circulation,1998,98 (20):2108-2116.
  • 8Banai S,Jaklitsch MT,Shon M,et al.Agiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs[J].Circulation,1994,89 (5):2183-2189.
  • 9Moulton KS,Heller E,Konerding MA,et al.Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprctein E-deficient mice[J].Circulation,1999,99 (13):1726-1732.
  • 10王长谦,汤大鸣,王利民,谢秀兰,徐依敏,丁泓毅,宋伟,王彬尧,黄定九.VEGF对人血单核细胞基质金属蛋白酶表达及活性的影响[J].心脏杂志,2004,16(4):308-311. 被引量:6

二级参考文献13

  • 1Falk E, Shah PK, Fuster V. Coronary plaque disruption[J].Circulation, 1995, 92: 657-667.
  • 2Galis ZS, Sukhova GK, Libby P. Microscopic localization of active proteinases by in situ zymography: detection of matrix metalloproteinase activity in vascular tissue[J]. FASEB J,1995, 9: 974-980.
  • 3Murphy G, Willenbrock F, Crabbe T, et al. Regulation of matrix metalloproteinase activity[J]. Ann N Y Acad Sci, 1994,732: 31-41.
  • 4Moreau M, Brocheriou I, Petit L, et al. Interleukin-8 mediates downregulation of tissue inhibitor of metalloproteinase-1 expression in cholesterol-loaded human macrophages: relevance to stability of atherosclerotic plaque[J]. Circulation, 1999,99:420-426.
  • 5Inoue M, Itoh H, Ueda M, et al. Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions: Possible pathophysiological significance of VEGF in progression of atherosclerosis[J]. Circulation, 1998, 98: 2108-2116.
  • 6Cuici JA, Mao DL, Bohner DG, et al. Preoperative treatment with doxycycline reduces aortic wall expression and activation of matrix metalloproteinases in patients with abdominal aortic aneurysms[J]. J Vasc Surg,2000, 31: 325-342.
  • 7Xu XP, Meisel SR, Ong JM, et al. Oxidized low-density lipoprotein regulates matrix metalloproteinae-9 and its tissue inhibitor in human monocyte-derived macrophages [J]. Circulation,1999,99: 993-998.
  • 8Beck L Jr, D'Amore PA. Vascular development: cellular and molecular regulation[J]. FASEB J, 1997, 11: 365-373.
  • 9Wang H, Moore S, Alavi MZ. Synthesis of tissue inhibitor of metalloproteinase-1 (TIMP-1) in rabbit aortic neointima after selective de-endothelialization[J]. Atherosclerosis, 1996, 126:95-104.
  • 10Unemori EN, Ferrara N, Bauer EA, et al. Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells[J]. J Cell Physiol, 1992, 153: 557-562.

共引文献5

同被引文献74

引证文献5

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部