精子的获取方式对ICSI治疗后妊娠结局的影响

Effect of the Manner of Acquired Spermatozoa on Pregnancy Outcome after Intracytoplasmic Sperm Injection

目的探讨不同方式获取的精子对卵胞浆内单精子注射术(ICSI)治疗后妊娠结局的影响。方法根据获取精子的方式不同将有或无精子症患者分为3组:射出精子组129例、附睾精子组65例和睾丸精子组11例。3组患者均行ICSI治疗。观察3组受精、卵裂、优质胚胎及临床妊娠等情况。结果射出精子组的受精率、卵裂率、优质胚胎率及临床妊娠率与附睾精子组、睾丸精子组比较差异均无统计学意义(均P>0.05)。结论在ICSI周期使用不同来源的精子,不影响其受精和妊娠结局。

Objective To explore the effect of different manner of acquired spermatozoa on pregnancy outcome after intracytoplasmic sperm injection （ICSI）. Methods spermatozoa or azoospermia in patients were according to different manner of acquired spermatozoa divided into 3 groups ： ejaculates spermatozoa group （n = 129 ）, epididymal spermatozoa group （n = 65） and testicular spermatozoa group（n： 11） . Three groups of patients were treated by ICSI. Observed groups 3 the fertilization,embryo cleavage,good quality embryo and clinical pregnancy. Results The ejaculates spermatozoa group of fertilization rates, embryo cleavage rates, good quality embryo rates and clinical pregnancy rates were compared with epididymal spermatozoa group and testicular spermatozoa group. There was not significant difference among three groups （all P〉 0.05）. Conclusion There was not significant difference in fertilization and pregnancy outcome in ICSI cycles using different source of spermatozoa.