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抗肿瘤药物多柔比星脂质体 被引量:25

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摘要 多柔比星(Doxombicin)是1969年从松链丝菌浅灰色变株(Str.peucetius var.caesius)中提取分离到的蒽环类抗生素,具有很强的抗癌活性,化疗指数较高,临床上单独使用或与其他抗癌药物联合使用可有效治疗各种恶性肿瘤。多柔比星属于细胞周期非特异性药物,它主要通过嵌入DNA碱基对之间并与DNA紧密结合,从而阻止DNA的复制,抑制DNA依赖性多聚酶的作用,干扰RNA转录过程。
作者 谢雨礼 苏红
出处 《药学与临床研究》 2010年第2期107-111,共5页 Pharmaceutical and Clinical Research
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参考文献40

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二级参考文献3

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