期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

乳腺癌肿瘤细胞中趋化因子CXCL12及其受体CXCR4的研究进展

Review of Chemotactic Factor CXCL12 and Its Receptor CXCR4 in Breast Cancer
下载PDF
导出
摘要 CXCL12因子及其受体CXCR4作为趋化因子家族中与肿瘤关系最为密切的一对,特别在乳腺癌方面,无论是对原位肿瘤还是转移性肿瘤都进行了一系列深入的研究,本文就这一方面的研究进行了总结和展望。 CXCL12 and its receptor CXCR4, the most related to cancer in chemokine family, have been extensively studied and they were found participating in the occurrence and developing processes of various tumors, especially for breast cancer, no matter tumors in situ or metastatic. This article is a summary and outlook of the research which has been done on the CXCL12 and its receptor CXCR4 in breast cancer.
作者 刘小林 蔡宁 童本定
机构地区 江苏省肿瘤医院
出处 《药学与临床研究》 2010年第2期120-122,共3页 Pharmaceutical and Clinical Research
关键词 乳腺癌 CXCR4 CXCL12 Breast cancer CXCR4 CXCL12
分类号 R937.9 [医药卫生—生药学]
  • 相关文献

参考文献12

  • 1Balkwill F.The significance of cancer cell expression of the chemokine receptor CXCR4[J].Seminars Cancer Biol,2004,14(3):171-9.
  • 2Struyf S,Proost P,Van Damme J.Regulation of the immune response by the interaction of chemokines and proteases[J].Adv Immunol,2003,81(1):1-44.
  • 3Koizumi K,Hojo S,Akashi T,et al.Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response[J].Cancer Sci,2007,98(11):1652-8.
  • 4Fernandis AZ,Prasad A,Band H,et al.Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells[J].Oncogene,2004,23(1):157-67.
  • 5Salvucci O,Yao L,Villalba S,et al.Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1[J].Blood,2002,99(8):2703-11.
  • 6Smith MC,Luker KE,Garbow JR,et al.CXCR4 regulates growth of both primary and metastatic breast cancer[J].Cancer Res,2004,64(23):8604-12.
  • 7Lapteva N,Yang AG,Sanders DE,et al.CXCR4 knockdown by small interfering RNA abrogates breast tumor growth in vivo[J].Cancer Gene Ther,2005,12(1):84-9.
  • 8Muller A,Homey B,Soto H,et al.Involvement of chemokine receptors in breast cancer metastasis[J].Nature,2001,410(6824):50-6.
  • 9Kang Y,Siegel PM,Shu W,et al.A multigenic program mediating breast cancer metastasis to bone[J].Cancer Cell,2003,3(6):537-49.
  • 10Staller P,Sulitkova J,Lisztwan J,et al.Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL[J].Nature,2003,425(6955):307-11.
药学与临床研究
2010年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部