高危新生儿脑干听觉诱发电位的近期观察

Study on Auditory Brainstem Responses in High-Risk Neonates.

目的 为了解高危新生儿脑干及听觉功能障碍情况.方法 于1995年8月～1996年1月对128例高危新生儿进行脑干听觉诱发电位(Anditory Brainstem Responses—ABR)测定.结果 急性期高危新生儿ABR异常率为51.4%,其中高胆红素血症,低体重儿,窒息和丁胺卡那霉素应用组ABR异常率分别为61.1%、66.7%、53.8%和 2.8%.血清胆红素(Sb)值>290.7μmol/L和重度窒息儿ABR异常率明显高于Sb<290.7μmol/L和轻度窒息儿.早产儿和足月小样儿ABR异常率无明显差异.丁卡组对听阀的近期影响不大.结论 高危新生儿是脑干和听觉功能障碍的高危人群,应当密切随防和早期干预.

Objective In order to study the changes of Auditory Brainstem Responses (ABR) in high-risk neonates. Methods 128 high-risk neonates were selected for ABR analysis. Results The incidence of ABR abnormality in acute stage of high-risk neonates is 51. 4%. The incidence of ABR abnormality in hyperbilirubinemia,low-birth weight infants, perinatal asphyxia and those exposed to ototoxic medicine(amikacin)is 61.1%,66. 7%,53. 8% and 2. 8% respectively. The rate of ABR abnormality of those with serum bilirubin (sb) level >290. 7μmol/L and severe asphyxia is much higher than those with sb level <290. 7μmol/L and mild asphyxia. There is no statistical significant difference ( P >0. 05) between the preterm infants and term infants. There is not much effect on the hearing threshold in the Amikacin group. Conclusion High-risk neonates are the high-risk population of hearing lose and brainstem problem who must be followed-up closely. The interference should be given early.