摘要
目的 为了探讨婴儿先天缺陷危险因素.方法 对191例先天缺陷婴儿采用1:2病例对照研究方法,经单因素、多因素Logistic回归分析.结果 显示先天缺陷婴儿的主要危险因素是:家族先天缺陷史,孕早期病毒感染、用药、接触有害物质和自然流产史.相对危险比值比分别为:28.92、62.50、5.58、4.10、2.39.结论 加强围产保健,对遗传和环境因素影响值得进一步研究.
Objective To research the risk factor of congenital defect of infants. Methods A case-control study on congenital defect of 191 infants. According to one case was matched to two normal infants,analysis of simple factor and muliple factor loglistic regression were taken. Results Main risk factors of congenital defect of infants were: family history of congenital defect, during the early pregnancy virus infection,administrating medicine ,exposing to harmful environment and spontaneous abortion. The odds ration (OR) were 28. 92,62. 50,5. 58,4. 10,2. 39 respectively. Conclusions Enhancing pregnancy hygiene. Further studying genetic and en-vivonmental factors were deserved.
关键词
婴儿
先天缺陷
危险因素
Infant Congenital defect Risk factors
