恶性肿瘤化疗患者医院真菌感染的临床分析

Clinical feature of fungal infection in cancer patients received chemotherapy

目的:了解恶性肿瘤化疗患者医院真菌感染的临床特点。方法:对我院2006年10月-2008年10月68例发生医院真菌感染的恶性肿瘤化疗患者资料资料进行回顾性分析。结果:恶性肿瘤化疗患者医院真菌感染率为3.1%,真菌感染发生部位依次为呼吸道(60.3%)、消化道(22%)、泌尿道(10.3%)等,病原体主要为白色假丝酵母菌(63.2%)、热带假丝酵母菌(14.7%)、光滑假丝酵母菌(7.3%)、克柔假丝酵母菌(5.8%)。结论:恶性肿瘤化疗后患者真菌感染以呼吸道部位最多、白色假丝酵母菌为主要病原体。

Objective：To describe the clinical features of fungal infections among cancer patients who received chemotherapy. Methods： Sixty- eight cases of fungal infections, which were diagnosed in cancer patients received chemotherapy from October 2006 to October 2008, were analyzed retrospectively. Results： The fungal infection rate among those patients was 3.1%. The infection sites were respiratory tract （60.3 % ）, digestive tract （22%）, urinary tract（ 10.3% ）. The common pathogens were C. albicans （ 63.2% ）, C. tropicalis （ 14.7% ）, C. glabrata （7.3%）. Conclusion ： Among fungal infection of the cancer patients received chemotherapy, respiratory tract was the most com- mon infection site, and C. albicans was the prevalent pathogen.