青少年甲状腺癌20例临床分析

Clinical analysis of 20 adolescent cases with thyroid carcinoma

为总结近年青少年甲状腺癌的临床特点、诊断和治疗方法。回顾性分析烟台毓璜顶医院甲状腺外科1990-2007年收治的≤18岁青少年甲状腺癌患者20例。其中,乳头状腺癌17例,滤泡状癌2例,乳头滤泡状癌1例,均行手术治疗。患侧腺叶加峡部切除2例,患侧腺叶加峡部切除及对侧大部切除18例,单侧功能性颈淋巴结清除术13例,双侧颈部淋巴结清除术2例,术后病理示颈淋巴结转移15例。所有患者术后均予甲状腺素抑制治疗。平均随访8年(1～16年),5年生存率100.0%,获10年随访患者10年生存率85.7%。初步研究结果提示,青少年甲状腺癌预后良好,正确的诊断和恰当的治疗是取得长期生存的关键。

The objective of this study was to analysis the clinical characteristics,diagnosis,treatment and prognosis of adolescent thyroid carcinoma. A total of 20 cases of adolescent thyroid carcinoma under 18 years old between 1990 and 2007 in thyroid department of Yantai Yuhuangding Hospital were reviewed. The pathology after surgery revealed papillary carcinoma 17 cases,follicular carcinoma 2 cases,papillary and follicular carcinoma 1 case. All patients were underwent surgical treatment,consisted of a lobectomy in 2 cases,subtotal thyroidectomy in 18 cases. Single cervical lymphadenectomy in 13 cases and bilateral cervical lymphadenectomy in 2 cases. Cervical lymph node metastasis was found in 15 cases. All patients received postoperative thyroid hormone suppressive therapy. The follow-up period was 1 to 16 years with a median span 8 years. The 5-year survival rate was 100.0%,and 10-year survival rate was 85.7%. Preliminary research result show that the prognosis of adolescent thyroid cancer is considerable good. Correct diagnosis and treatment are important for long survival.