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L-ficolin基因Thr236Met位点多态性与儿童反复呼吸道感染的相关性 被引量：1

Association between L-ficolin Thr236Met polymorphism and recurrent respiratory tract infection in children
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摘要 目的探讨中国江苏汉族儿童L-ficolin基因Thr236Met位点多态性与反复呼吸道感染的相关性。方法采用碱基淬灭探针技术检测104例反复呼吸道感染患儿及214例对照组儿童L-ficolin基因Thr236Met位点多态性。结果L-ficolin基因Thr236Met多态性基因型和等位基因频率分布在反复呼吸道感染组和对照组比较差异无统计学意义(P>0.05)。结论中国江苏汉族儿童反复呼吸道感染的发病与L-ficolin基因Thr236Met位点多态性没有关联。 Objective To investigate the association between the Thr236Met polymorphism in the L-ficolin gene and recurrent respiratory tract infection（RRTI） in Chinese Han children of Jiangsu.Methods The genotypes of Thr236Met polymorphism in the L-ficolin gene were detected using base-quenched probe technique in 104 RRTI children and 214 controls.Results There was no significant difference in frequencies of genotype and allele in Thr236Met polymorphism between RRTI and the controls group （P0.05）.Conclusion The L-ficolin Thr236 Met polymorphism is not associated with RRTI in Chinese Han children of Jiangsu.
作者 王劲波 王永清 罗光华 张俊 牟琴峰 杨晓宇
机构地区 苏州大学附属第三医院(常州市第一人民医院)儿科
出处 《江苏医药》 CAS CSCD 北大核心 2010年第6期666-668,共3页 Jiangsu Medical Journal
关键词 反复呼吸道感染 L-ficolin基因 多态性 单核苷酸 Recurrent respiratory tract infection L-ficolin Polymorphism Single nucleotide
分类号 R725 [医药卫生—儿科]
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参考文献11

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共引文献319

同被引文献11

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江苏医药
2010年 第6期

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