摘要
目的:回顾性比较后腹腔镜上尿路移行细胞癌根治术(LNU)与开放性上尿路移行细胞癌根治术(ONU)患者的临床资料,探讨后腹腔镜联合下腹部Glison切口治疗上尿路移行细胞癌手术的临床价值。方法:回顾性分析88例经病理检查证实的上尿路移行细胞癌患者临床资料,其中42例行LNU,46例行0NU,采用t检验比较患者术中出血、术后恢复时间等资料,采用Kaplan-Meier法比较生存率,采用log-rank检验法比较组间生存率。结果:两组间平均手术时间差异无统计学意义,LNU组术中失血量、术后肠道恢复时间及住院时间明显少于ONU组,INU组和ONU组5年总生存率分别为81.0%和73.7%(P=0.689),两者之间差异无统计学意义。结论:后腹腔镜联合下腹部Glison切口治疗上尿路上皮肿瘤创伤小,安全有效,可达到与开放手术相同的肿瘤控制效果,可部分替代开放性上尿路上皮肿瘤根治术。
Objective:To compare retrospectively the clinical data of laparoscopic nephroureterectomy (LNU) and standard open surgery (ONU) for upper urinary tract transitional cell carcinoma, and to contrast the efficacy of retroperitoneal laparoscopic combine with lower abdominal glison incision for urinary tract transitional cell carcinoma. Methods:88 patients who underwent nephroureterectomy for upper tract transitional cell carcinoma were enrolled for reviewing. Of the 88 patients, forty-two were treated with LNU, and the other forty-six were with ONU. T test were used for comparing blood loss, hospital stay, and Kaplan-Meier and log-rank were used for comparing survival rate and survival rates between the groups. Resuits The average operating time between the two groups was no significant difference, the average blood loss, hospital stay were significantly lower in LNU, comparing with that of ONU. the 5--year overall survival rates of LNU group and ONU group of were 81 . 0% and 73 . 7% ( P = 0 . 689), no statistically significant difference between the two groups. Conelusions Retroperitoheal laparoseopic combine with lower abdominal glison incision/or urinary tract transitional cell carcinoma was invasive, safe and effective, and it can be achieved the control effects as open surgery with the same tumor. It may replace open radical surgery on the urinary tract epithelial tumor.
出处
《临床泌尿外科杂志》
北大核心
2010年第3期176-178,181,共4页
Journal of Clinical Urology