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核因子κB抑制剂对肿瘤化疗、免疫治疗增敏及抑制转移作用研究进展

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摘要 在肿瘤的治疗过程中,耐药、复发及转移等情况的发生是很常见、也是很棘手的问题,目前有关癌细胞发生这些变化的分子机制研究是国际上的热点和前沿。近些年,以VanWaes等和Karin等为代表的很多研究证实了核因子κB（NF—κB）所调控的基因在癌细胞增殖、浸润、新生血管形成、耐药、转移等多个方面都起到了重要的作用，
作者 贾强 孟召伟 谭建
机构地区 天津医科大学总医院核医学科
出处 《天津医药》 CAS 北大核心 2010年第4期345-347,共3页 Tianjin Medical Journal
基金 国家自然科学基金青年基金项目(项目编号:30900376) 天津医科大学科研基金(项目编号:2008KY20) 天津市应用基础及前沿技术研究重点项目(项目编号:10JCZDJC19000)
关键词 NF-κB 肿瘤 化学疗法 肿瘤 局部灌注 免疫疗法 免疫耐受 肿瘤转移
分类号 R28 [医药卫生—中药学]
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参考文献19

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二级参考文献10

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天津医药
2010年 第4期

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