不孕症中医体质流行病学调查及相关研究

Epidemiological Investigation of Constitution of Sterility Patients

目的:探讨不孕症中医体质分布以及其与证候的相关性。方法:调查对象分为不孕症组200例和正常组212例,调查人员直接询问被调查者,填写《一般情况调查表》和《中医体质量表》,对2组进行体质测评。结果:不孕症体质类型主要为阳虚质、痰湿质、阴虚质,构成比分别为29.5%、20.0%和21.0%。不孕症组阳虚质、气虚质、阴虚质所占比例均高于正常组,差异有显著性意义(P<0.05)。肾虚证与阴虚质、阳虚质,血瘀证与瘀血质、阳虚质,肝郁证与痰湿质、湿热质,痰湿证与痰湿质相关程度较高;而气虚质与4种证候均相关。体质因素对不孕症证候的影响始终都是显著的,而气虚质与痰湿证、肝郁证、血瘀证、肾虚证的形成均显著相关。瘀血质仅与血瘀证密切相关,只易产生血瘀证候。结论:不孕症发病及其发病后的证候类型均与体质相关。

Objective:To explore the relationship between constitution distribution in sterility patients and syndromes patterns.Methods:The general data and traditional Chinese medical constitution scale items were collected from 200 sterility patients and 212 healthy volunteers.Then the constitution distribution in sterility patients was investigated.Results:The constituent ratio of yang deficiency,phlegm-damp constitution,and yin deficiency was 29.5%,20.0% and 21.0% respectively in sterility patients.The percentages of yang deficiency constitution,Qi deficiency constitution,and yin deficiency constitution in sterility patients were higher than those in the normal control group,the differences being significant between the two groups (P < 0.05).Kidney deficiency syndrome was positively correlated with yin deficiency constitution and yang deficiency constitution,blood-stasis syndrome was positively correlated with blood-stasis constitution and yang deficiency constitution,liver stagnation syndrome was positively correlated with phlegm-damp constitution and damp-heat constitution,and phlegm-damp syndrome was positively correlated with phlegm-damp constitution.Qi deficiency constitution was correlated with the above 4 syndrome patterns.Constitution had an obvious effect on the syndrome patterns of sterility patients.Qi deficiency constitution was correlated with the syndrome patterns of phlegm damp,liver stagnation,kidney deficiency and blood stasis.Blood stasis constitution was correlated with the blood-stasis syndrome.Conclusion:The onset of sterility and the syndrome patterns of sterility are correlated with the constitution.