耐药肺结核185例耐药性分析

MDR-TB Drug Resistance Analysis of 185 Cases

目的了解耐药性肺结核病人在抗结核治疗过程中的耐药情况及其变化趋势。方法对确诊的185例耐药性肺结核病人的耐药菌株,进行治疗前、后药敏结果的比较和分析,并统计质量前后耐药菌谱变化情况。结果本组185例中初始耐药率为23.78%,获得性耐药率为76.22%;初始耐多药率14.05%,获得性耐多药率61.08%。结论对耐药性肺结核患者的耐药菌株进行适时检测其耐药谱、获取全面的药敏资料具有较大的意义。

Objective To understand the status and trend of drug resistance of ruultidrug-resistance pulmonary tuberculosis during treatment. Methods The drug resistance between the first and last drug sensitivity test was compared in 185 muhidrug-resistance pulmonary tu- berculosis patients before and after treatment. Results In this group of 185 patients with initial drug resistance rate was 23.78% ,acquired drug resistance rate was 76.22%; the initial multi-drug resistant rate of 14.05% ,acquired multi-drug resistant rate of 61.08%. Conclusion For the multidrug-resistance pulmonary tuberculosia patients, the supervision of drug resistance can play practical significance in anti-tuberculosis treatment before and during the treatment.