超声造影在妇科附件区包块诊断中的应用

Application of contrast-enhanced ultrasound in diagnosis of annex lesions

目的探讨超声造影在附件区包块诊断与鉴别诊断中的应用价值。方法对110例附件区包块的患者同时应用阴道超声、彩色多普勒超声及超声造影检查,将各组造影声像图进行观察并与术后病理结果进行对比。结果超声造影检查判断附件区包块良恶性的灵敏度为96.1%,特异度98.4%,阳性预测值98.0%,阴性预测值96.8%,准确度97.3%,明显高于其它3种方法(P<0.05);良性组始增时间、达峰时间分别为(19.45±4.76)s、(38.00±28.22)s,较恶性组(15.18±5.38)s、(28.40±7.94)s,明显延长(P<0.05);而消退时间良性组为(188±30.35)s,较恶性组(246±40.86)s,明显缩短(P<0.05)。结论超声造影检查具有灵敏度高、特异性强、准确率高等特点,对附件区包块良恶性的诊断与鉴别诊断有很好的辅助作用,具有广泛的临床意义和应用价值。

Objective To observe the application of ultrasound contrast agent SonoVue in diagnosis and differential diagnosis of annex lesions.Methods 110 patients with annex lesions in our hospital admitted transvaginal sonography and color Doppler ultrasound and contrast-enhanced ultrasound examination,and then observed the contrast-enhanced ultrasound dynamic image and contrast with pathological results.Results Contrast-enhanced ultrasound was used for determination in the annex area of benign and malignant mass,the results showed that sensitivity was 96.1%,specificity was 98.4%,positive predictive value was 98.0%,negative predictive value was 96.8% and accuracy was 97.3%.And they were significantly higher than those by other three methods.Start enhance time,time-to peak of benign group was respectively 19.45±4.76s and 38.00±28.22s;and in malignant group,it was 15.18±5.38s and 28.40±7.94s,and it was longer in benign group than that in malignant group（P0.05）.Wash-out time was 188±30.35s in benign group and 246±40.86s in malignant group,and it was shorter in benign group than that in malignant group（P0.05）.Conclusion Contrast-enhanced ultrasound examination with high sensitivity,specificity and high accuracy,and helpful for improving the confidence to the differential diagnosis of benign and malignant annex lesion.